Ambulatory PA Pressure Monitoring in Heart Failure: Concepts and Controversies
Our co-hosts interview Jacob Abraham, MD, about navigating the concepts and controversies surrounding Ambulatory PA Pressure Monitoring for heart failure patients. On "From Failure to Function" Priya discusses CRISPR gene editing of CaMKII for cardio-protection, and on HF Rounds, Michael reviews keys for the implementation of exercise training in heart failure patients.
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Hosts:
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Michael Beasley, MD, Assistant Professor of Medicine at the Yale School of Medicine @MHBeasleyMD
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Priya Umapathi, MD, Assistant Professor in the Division of Cardiology & Advanced Heart Failure and Heart Transplant Cardiologist at Johns Hopkins Hospital @priyaumapathi
Guest:
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Jacob Abraham, MD, Section Head, Advanced Heart Failure at Providence St. Vincent Medical Center @Abraham_Jacob
References
- Dibben GO, Hannay JR, Taylor RS. Exercise training in heart failure. Heart Published Online First: 17 July 2023. doi: 10.1136/heartjnl-2022-321132
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Takahiko Nishiyama et al. ,Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy. Sci. Transl. Med. 14, eade1633 (2022). DOI:10.1126/scitranslmed.ade1633
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Lebek S, Chemello F, Caravia XM, Tan W, Li H, Chen K, Xu L, Liu N, Bassel-Duby R, Olson EN. Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease. Science. 2023 Jan 13;379(6628):179-185. doi: 10.1126/science.ade1105. Epub 2023 Jan 12. PMID: 36634166; PMCID: PMC10150399.
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Abraham J, Bharmi R, Jonsson O, et al. Association of Ambulatory Hemodynamic Monitoring of Heart Failure With Clinical Outcomes in a Concurrent Matched Cohort Analysis. JAMA Cardiol. 2019;4(6):556–563. doi:10.1001/jamacardio.2019.1384
Guest Disclosures
Speaker's honoraria, consultant, scientific steering committee member (INTELLECT2, MitraClip/CardioMEMS study) - Abbott
Co-founder HF2, academic research consortium