Challenging Amyloid Management: Unveiling the Curtain Behind the Wizard of Oz

This session will explore the complex landscape of amyloidosis, focusing on its detection using contemporary tools, the evolving natural history in the current therapeutic era, and strategies to manage all stages of disease in a cost-efficient and patient-centered manner.

Learning Objectives

• Review disease trajectory, including strategies to improve diagnosis and assess progression.
• Describe the cost–benefit ratio of emerging drug therapies in cardiac amyloidosis, with a focus on ATTR.
• Describe the approach to and outcomes of heart transplantation in cardiac amyloidosis, with a specific focus on multiorgan transplantation and light chain versus myeloma-related considerations.